What is the Succinimide?

Succinimide is A white crystalline powder, while it's Molecular Formula is C4H5NO2. A white crystalline powder Succinimide is used in organic syntheses and in industrial silver plating processes. It is a reagent that is used in the synthesis of Lumiflavin (L473900), which is a toxic photolysis product of vitamin B2 (R415000). Further, it is used to form covalent bonds between proteins, peptides and plastics. In addition to this, it is used as an important raw material for the synthesis of heterocyclic compounds through N-acyliminium cyclizations.

What is the CAS number for Succinimide?

The CAS number of Succinimide is 123-56-8.

What is Succinimide (123-56-8) used for?

Succinimide is a natural product found in Xanthium strumarium and Panax notoginseng with data available.Succinimide is a colorless acicular crystal or thin solid with light brown luster. It tastes sweet. Easily soluble in water, alcohol or sodium hydroxide solution, insoluble in ether, chloroform, etc. Succinimide dispersants appear as dark or brown-colored liquids with a thickness or viscosity similar to heavy syrup. They have little or no solubility in water, and because they are denser than water, will sink in a water environment. They are readily soluble in oil and lighter weight hydrocarbons, such as gasoline. Succinimide dispersants have very low vapor pressure and little noticeable odor at ambient temperatures.InChI:InChI=1/C4H5NO2/c6-3-1-2-4(7)5-3/h1-2H2,(H,5,6,7)

What is the Succinimide?

Succinimide is A white crystalline powder, while it's Molecular Formula is C4H5NO2. A white crystalline powder Succinimide is used in organic syntheses and in industrial silver plating processes. It is a reagent that is used in the synthesis of Lumiflavin (L473900), which is a toxic photolysis product of vitamin B2 (R415000). Further, it is used to form covalent bonds between proteins, peptides and plastics. In addition to this, it is used as an important raw material for the synthesis of heterocyclic compounds through N-acyliminium cyclizations.

What is the CAS number for Succinimide?

The CAS number of Succinimide is 123-56-8.

What is Succinimide (123-56-8) used for?

Succinimide is a natural product found in Xanthium strumarium and Panax notoginseng with data available.Succinimide is a colorless acicular crystal or thin solid with light brown luster. It tastes sweet. Easily soluble in water, alcohol or sodium hydroxide solution, insoluble in ether, chloroform, etc. Succinimide dispersants appear as dark or brown-colored liquids with a thickness or viscosity similar to heavy syrup. They have little or no solubility in water, and because they are denser than water, will sink in a water environment. They are readily soluble in oil and lighter weight hydrocarbons, such as gasoline. Succinimide dispersants have very low vapor pressure and little noticeable odor at ambient temperatures.InChI:InChI=1/C4H5NO2/c6-3-1-2-4(7)5-3/h1-2H2,(H,5,6,7)

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123-56-8

Product Name：Succinimide
Molecular Formula：C₄H₅NO₂
Purity：99%
Molecular Weight：99.0892

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Product Details;

CasNo： 123-56-8

Molecular Formula： C₄H₅NO₂

Appearance： A white crystalline powder

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Molecular Formula:C4H5NO2
Molecular Weight:99.0892
Appearance/Colour:A white crystalline powder
Vapor Pressure:0.0024mmHg at 25°C
Melting Point:123-125°C
Refractive Index:1.479
Boiling Point:288 °C at 760 mmHg
PKA:9.6(at 25℃)
Flash Point:160 °C
PSA：46.17000
Density:1.274 g/cm³
LogP:-0.24820

Succinimide(Cas 123-56-8) Usage

Description	Succinimide is described as a natural product found in plants such as Xanthium strumarium and Panax notoginseng. It is a colorless acicular crystal or thin solid with a light brown luster. It has a sweet taste and is easily soluble in water, alcohol, or sodium hydroxide solution. However, it is insoluble in solvents like ether and chloroform. Succinimide dispersants are dark or brown-colored liquids with a viscosity similar to heavy syrup. They have limited or no solubility in water, and they are denser than water, causing them to sink in a water environment.
Chemical Properties	white crystalline powder
Uses	Succinimide is a cyclic imide of succinic acid and is present in various biologically active compounds, including anticonvulsants, antitremor agents, and anti-Parkinson's agents. It is a key intermediate for deamidation of asparagine (Asn) and isomerization of aspartic acid (Asp) residues in proteins or peptides, both in vivo and in vitro.
Definition	ChEBI: Succinimide is a dicarboximide that is pyrrolidine which is substituted by oxo groups at positions 2 and 5. It is a pyrrolidinone and a dicarboximide.
Consumer Uses	ECHA has no public registered data indicating whether or in which chemical products the substance might be used. ECHA has no public registered data on the routes by which this substance is most likely to be released to the environment.

InChI:InChI=1/C4H5NO2/c6-3-1-2-4(7)5-3/h1-2H2,(H,5,6,7)

123-56-8 Relevant articles

Accumulation of Succinimide in a Recombinant Monoclonal Antibody in Mildly Acidic Buffers Under Elevated Temperatures

Grace C. Chu, Dirk Chelius, Gang Xiao, Hui K. Khor, Sururat Coulibaly & Pavel V. Bondarenko

, Pharmaceutical Research volume 24, pages1145–1156 (2007)

Direct evidence that isoD30 was from succinimide was obtained by performing succinimide hydrolysis in H218O followed by tryptic digestion in H216O .

Generalized Chemoselective Transfer Hydrogenation/Hydrodeuteration

Wang, Yong,Cao, Xinyi,Zhao, Leyao,Pi, Chao,Ji, Jingfei,Cui, Xiuling,Wu, Yangjie

supporting information, p. 4119 - 4129 (2020/08/10)

A generalized, simple and efficient tran...

Propensity for spontaneous succinimide formation from aspartyl and asparaginyl residues in cellular proteins

STEVEN CLARKE

, Chemical Biology and Drug Design, Volume30, Issue6 December 1987 Pages 808-821

This reaction results in the formation of succinimide derivatives and has been shown to be largely responsible for the racemization, isomerization, and deamidation of these residues in several peptides under physiological conditions (Geiger, T. & Clarke, S. J. Biol. Chem. 262, 785–794 (1987)).