1480-19-9
- Product Name：Fluanisone
- Molecular Formula：C21H25 F N2 O2
- Purity：99%
- Molecular Weight：356.44
Product Details;
CasNo： 1480-19-9
Molecular Formula： C21H25 F N2 O2
Hot Sale High Purity Fluanisone 1480-19-9 In Stock
- Molecular Formula:C21H25 F N2 O2
- Molecular Weight:356.44
- Vapor Pressure:1.38E-10mmHg at 25°C
- Melting Point:67.5-68.5°
- Boiling Point:511.8°Cat760mmHg
- PKA:7.43±0.10(Predicted)
- Flash Point:263.3°C
- PSA：32.78000
- Density:1.146g/cm3
- LogP:3.62230
Fluanisone(Cas 1480-19-9) Usage
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Originator |
Sedalande ,J and J |
| Description | Fluanisone is a medication belonging to the butyrophenone class, which serves multiple purposes in the field of medicine. The synthesis of fluanisone involves several chemical reactions. One of the key steps in the synthesis process is the reaction of aluminum chloride, carbon disulfide, fluorobenzene, and γ-chlorobutyryl chloride to obtain γ-chloro-p-fluorobutyrophenone. |
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Uses |
Fluanisone is classified as a typical antipsychotic and sedative. It is primarily used for the treatment of schizophrenia and mania. Fluanisone also has applications in veterinary medicine. It is used in combination with the μ-opioid agonist fentanyl, primarily as a veterinary anesthetic. Fluanisone is known for its sedative properties, which can help calm individuals with agitation and certain psychiatric conditions. Additionally, as an antipsychotic medication, it can effectively address the symptoms associated with schizophrenia and related disorders. |
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Therapeutic Function |
Neuroleptic |
InChI:InChI=1/C21H25FN2O2/c1-26-21-7-3-2-5-19(21)24-15-13-23(14-16-24)12-4-6-20(25)17-8-10-18(22)11-9-17/h2-3,5,7-11H,4,6,12-16H2,1H3
1480-19-9 Relevant articles
CNS-agent precursor: A simple and efficient synthesis of an antipsychotic drug fluanisone
Narsaiah, A. Venkat,Nagaiah,Devi, B. Karuna
, p. 829 - 832 (2012/11/07)
A therapeutic trial has been carried out on 50 patients, most of them being hospitalized, in order to compare the characteristics of a new benzamide, Sultopride, to those of a butyrophenone, Fluanisone, for the treatment of important and chronic agitation states.
CNS-Agent Precursor: A Simple and Efficient Synthesis of an Antipsychotic Drug Fluanisone
A. Venkat Narsaiah, B. Nagaiah, B. Karuna Devi
, Journal of Heterocyclic Chemistry, Volume49, Issue4 July 2012 Pages 829-832
An efficient synthesis of antipsychotic drug fluanisone has been carried out in seven steps with an overall yield of 32.2%. The synthesis was started from 4-fluorobenzaldehyde. All the reactions were very clean and the isolation of products was very easy.
1480-19-9 Upstream products
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1402042-55-0
4-(benzyloxy)-4-(4-fluorophenyl)-butan-1-ol
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