841205-47-8
- Product Name：Ostarine
- Molecular Formula：C19H14F3N3O3
- Purity：99%
- Molecular Weight：389.334
Product Details;
CasNo： 841205-47-8
Molecular Formula： C19H14F3N3O3
Good Producer In Bulk Supply Ostarine 841205-47-8 with Best Price
- Molecular Formula:C19H14F3N3O3
- Molecular Weight:389.334
- Boiling Point:632.3±55.0 °C(Predicted)
- PKA:12.13±0.29(Predicted)
- PSA：106.14000
- Density:1.41±0.1 g/cm3(Predicted)
- LogP:3.29026
Ostarine (Cas 841205-47-8) Usage
|
description |
Ostarine, also known as MK-2866, is a selective androgen receptor modulator (SARM) with various potential applications. Ostarine is classified as a SARM, which means it is a compound that selectively targets and binds to androgen receptors in the body. |
|
Uses |
Ostarine has been studied for its potential use in medical treatments. It has been investigated in clinical trials for conditions like stress urinary incontinence and triple-negative breast cancer. Ostarine is sometimes used by athletes, bodybuilders, and fitness enthusiasts to enhance muscle growth and improve physical performance. It is often taken orally as a supplement. |
InChI:InChI=1/C19H14F3N3O3/c1-18(27,11-28-15-6-2-12(9-23)3-7-15)17(26)25-14-5-4-13(10-24)16(8-14)19(20,21)22/h2-8,27H,11H2,1H3,(H,25,26)/t18-/m1/s1
841205-47-8 Relevant articles
Evaluation of ostarine as a selective androgen receptor modulator in a rat model of postmenopausal osteoporosis
D. B. Hoffmann, M. Komrakova, S. Pflug, M. von Oertzen, D. Saul, L. Weiser, T. A. Walde, M. Wassmann, A. F. Schilling, W. Lehmann & S. Sehmisch
, Journal of Bone and Mineral Metabolism volume 37, pages243–255 (2019)
We evaluated the effects of the SARM drug ostarine on postmenopausal osteoporotic bone in a rat osteoporosis model. Ovariectomy was performed on 46 of 56 3-month-old female Sprague–Dawley rats. Eight weeks after ovariectomy, ostarine was orally administered daily for 5 weeks in dosages of 0.04 (low, OVX + Ost. 0.04), 0.4 (intermediate, OVX + Ost. 0.4), and 4 mg/kg (high, OVX + Ost. 4) body weight.
Ostarine increases lean body mass and improves physical performance in healthy elderly subjects: Implications for cancer cachexia patients
W. Evans , M. R. Smith , J. E. Morley , K. G. Barnette , D. Rodriguez , M. S. SteinerJ. T. Dalton
Paragraph 0025; 0026, (2019/06/05)
We conducted a randomized phase II proof of concept study of ostarine, the first-in-class SARM, in healthy postmenopausal women and elderly men prior to intitiating a phase II study in cancer patients.
841205-47-8 Process route
-
- 767-00-0
4-cyanophenol
-
![(2R)-3-bromo-N-[4-cyano-3-(trifluoromethyl)phenyl]-2-hydroxy-2-methylpropanamide](/upload/2023/8/4661d345-a661-4e6b-979b-c6a9f0339ecf.png)
- 206193-17-1
(2R)-3-bromo-N-[4-cyano-3-(trifluoromethyl)phenyl]-2-hydroxy-2-methylpropanamide
-
- 1235370-13-4,841205-47-8
Enobosarm
| Conditions | Yield |
|---|---|
|
4-cyanophenol; With sodium hydride; In tetrahydrofuran; mineral oil; Inert atmosphere;
(2R)-3-bromo-N-[4-cyano-3-(trifluoromethyl)phenyl]-2-hydroxy-2-methylpropanamide; In tetrahydrofuran; mineral oil; at 20 ℃; for 24h; Inert atmosphere;
|
75% |
|
With potassium carbonate; In isopropyl alcohol; for 0.5h; Inert atmosphere; Reflux;
|
75.5% |
|
With potassium carbonate; In water; isopropyl alcohol; for 3h; Heating / reflux;
|
59.9% |
|
With potassium carbonate; In isopropyl alcohol; for 3h; Heating / reflux;
|
59.9% |
|
With potassium carbonate; In isopropyl alcohol; for 3h; Reflux;
|
59.9% |
|
With potassium carbonate; In isopropyl alcohol; for 3h; Reflux;
|
59.9% |
|
With potassium carbonate; In isopropyl alcohol; for 3h; Reflux;
|
59.9% |
|
With potassium carbonate; In isopropyl alcohol; for 3h; Reflux;
|
59.9% |
|
With sodium carbonate; In isopropyl alcohol; Reflux; Large scale;
|
-
- 767-00-0
4-cyanophenol
-
![(S)-(-)-3-bromo-2-hydroxy-2-methyl-N-[(4-cyano-3-(trifluoromethyl)phenyl)]propanamide](/upload/2023/8/45987232-9bc4-4126-a799-4fa286614440.png)
- 113181-02-5
(S)-(-)-3-bromo-2-hydroxy-2-methyl-N-[(4-cyano-3-(trifluoromethyl)phenyl)]propanamide
-
- 1132656-73-5,1235370-13-4,841205-47-8
(R)-N-(4-cyano-3-(trifluoromethyl)phenyl)-3-(4-cyanophenoxy)-2-hydroxy-2-methylpropanamide
| Conditions | Yield |
|---|---|
|
With potassium carbonate; In isopropyl alcohol; for 0.5h; Inert atmosphere; Reflux;
|
69.7% |
|
With potassium carbonate; In isopropyl alcohol; for 3h; Reflux;
|
59.9% |
841205-47-8 Upstream products
-
767-00-0
4-cyanophenol
-
206193-17-1
(2R)-3-bromo-N-[4-cyano-3-(trifluoromethyl)phenyl]-2-hydroxy-2-methylpropanamide
-
60-29-7
diethyl ether
-
344-25-2
D-Prolin
Relevant Products
-
FluanisoneCAS：1480-19-9
-
Methenolone enanthateCAS：303-42-4
-
Linocaine hydrochloride hydrateCAS：6108-05-0
