36127-17-0
- Product Name：2-(Carbomethoxy)-3-tropinone
- Molecular Formula：C10H10N2O4S
- Purity：99%
- Molecular Weight：197.234
Product Details;
CasNo： 36127-17-0
Molecular Formula： C10H10N2O4S
High Purity 99% 2-(Carbomethoxy)-3-tropinone 36127-17-0 Powder with Hot Sale Price
- Molecular Formula:C10H10N2O4S
- Molecular Weight:197.234
- Vapor Pressure:0.00166mmHg at 25°C
- Melting Point:104℃ (approx)
- Refractive Index:1.502
- Boiling Point:294.108 °C at 760 mmHg
- PKA:10.89±0.20(Predicted)
- Flash Point:131.672 °C
- PSA：46.61000
- Density:1.173 g/cm3
- LogP:0.14910
2-CARBOMETHOXY-3-TROPINONE(Cas 36127-17-0) Usage
|
Description |
2-Carbomethoxy-3-tropinone, also known as methylecgonine, is an advanced intermediate in the biosynthesis of cocaine. |
|
Uses |
2-carbomethoxy-3-tropinone is an intermediate in the synthesis of cocaine isomers at the cocaine receptor. It's important to note that 2-Carbomethoxy-3-tropinone is not typically encountered in a non-laboratory or non-illegal drug production setting, as it is an intermediate compound in the illegal production of cocaine. |
InChI:InChI=1/C10H15NO3/c1-11-6-3-4-7(11)9(8(12)5-6)10(13)14-2/h6-7,9H,3-5H2,1-2H3
36127-17-0 Relevant articles
Chemistry of the tropane alkaloids. 33. 2-Carbomethoxy-3-tropinone: an advanced intermediate in the biosynthesis of cocaine
E Leete
, Journal of the American Chemical Society, 1983
It is proposed that this ß-keto ester is converted to its methyl ester (3)prior to the subsequent reactions which involve dehydrogenation to the ¡minium salt 5 and cyclization …
Plant tropane alkaloid biosynthesis evolved independently in the Solanaceae and Erythroxylaceae
Jan Jirschitzka, Gregor W. Schmidt, Michael Reichelt, Bernd Schneider, Jonathan Gershenzon, and John Charles D’Auria dauria@ice.mpg.de
body text, p. 6762 - 6765 (2010/06/12)
Methylecgonone reductase reduces methylecgonone (2-carbomethoxy-3-tropinone) stereospecifically to 2-carbomethoxy-3β-tropine (methylecgonine), and has its highest activity, protein level, and gene transcript level in young, expanding leaves of E. coca.
Process for producing optically active tropinonemonocarboxylic acid derivative
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, (2008/06/13)
An optically active tropinonemonocarboxy...
36127-17-0 Process route
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- 100371-46-8
3-oxo-tropane-2,4-dicarboxylic acid dimethyl ester
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- 36127-17-0
(+/-)-2-(carbomethoxy)-3-tropinone
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- 532-24-1
tropinone
| Conditions | Yield |
|---|---|
|
With phosphate buffer; In water; at 20 ℃; for 24h; pH=8.0;
|
55% 13% |
-
- 532-24-1
tropinone
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- 616-38-6
carbonic acid dimethyl ester
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- 36127-17-0
(+/-)-2-(carbomethoxy)-3-tropinone
| Conditions | Yield |
|---|---|
|
With methanol; sodium hydride; In cyclohexane; for 1.75h; Heating;
|
80% |
36127-17-0 Upstream products
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638-37-9
butanedial
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78315-99-8
acetone-1,3-dicarboxylic acid mono-methyl ester
-
593-51-1
methylamine hydrochloride
-
532-24-1
tropinone
36127-17-0 Downstream products
-
43021-26-7
methyl 8-methyl-8-azabicyclo[3.2.1]oct-2-ene-2-carboxylate
-
46255-79-2
methyl (endo, endo)-3-hydroxy-8-methyl-8-azabicyclo<3.2.1>octan-2-carboxylate
-
7143-09-1
methyl (2-endo, 3-exo)-3-hydroxy-8-methyl-8-azabicyclo<3.2.1>octan-2-carboxylate
-
135-97-7
pseudotropine
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