121062-08-6

  • Product Name:Melanotan II
  • Molecular Formula:C50H69N15O9
  • Purity:99%
  • Molecular Weight:1024.19
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Product Details;

CasNo: 121062-08-6

Molecular Formula: C50H69N15O9

Appearance: solid

Quality products make an important contribution to long-term revenue and profitability. Best Quality Chinese Factory Supply Melanotan II 121062-08-6 In Stock

1.What is the Melanotan II ?

Melanotan II Acetic Acid Salt, is a lab-made chemical that is similar to a hormone found in people. Melanotan II has been shown to have melanogenesis (tanning) and aphrodisiac effects on humans.

C<sub>94</sub>H<sub>103</sub>N<sub>14</sub>O<sub>14</sub>PolS

C94H103N14O14PolS

acetic anhydride
108-24-7

acetic anhydride

Fmoc-(S)-2-aminohexanoic acid
77284-32-3,144701-20-2

Fmoc-(S)-2-aminohexanoic acid

melanotan-II
121062-08-6

melanotan-II

Conditions
Conditions Yield
C94H103N14O14PolS; With piperidine; benzotriazol-1-ol; In dichloromethane; N,N-dimethyl-d6-formamide; at 20 - 75 ℃; for 0.1h; rink-amide-MBHA resin Microwave irradiation;
Fmoc-(S)-2-aminohexanoic acid; With O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; N-ethyl-N,N-diisopropylamine; In dichloromethane; N,N-dimethyl-formamide; at 75 ℃; for 0.0833333h; rink-amide-MBHA resin Microwave irradiation;
acetic anhydride; Further stages;
 
Ac-Nle-Asp-His-D-Phe-Arg-Trp-Lys-NH<sub>2</sub>
117499-53-3

Ac-Nle-Asp-His-D-Phe-Arg-Trp-Lys-NH2

melanotan-II
121062-08-6

melanotan-II

Conditions
Conditions Yield
With dipotassium hydrogenphosphate; diphenyl phosphoryl azide; In N,N-dimethyl-formamide; 1) 0 deg C, 6 h, 2) r.t., overnight;
30%

2.What is the CAS number for Melanotan II ?

The CAS number of Melanotan II is 121062-08-6.

More information of Melanotan II 121062-08-6 are:

CAS Number

121062-08-6

Density

1.43 g/cm3

Refractive Index

1.669

HS CODE

3504009000

PSA

382.26000

LogP

3.60720

Pka

13.00±0.70(Predicted)

3.What are another words for Melanotan II ?

Synonyms for Melanotan II 121062-08-6:L-Lysinamide,N-acetyl-L-norleucyl-L-a-aspartyl-L-histidyl-D-phenylalanyl-L-arginyl-L-tryptophyl-, cyclic (2?;1,4,7,10,13,18-Hexaazacyclotricosane, cyclic peptide deriv.;17: PN:WO2006012667 PAGE: 40 claimed protein;19: PN: WO2008025074 SEQID: 19 claimedprotein;1: PN: WO2009033712PAGE: 103 claimed protein;2: PN: WO2006060873 SEQID: 2 claimed protein;MT II;PT 14;Melanotan-II;

4.What is the molecular formula of Melanotan II?

The chemical formula of  Melanotan II is C50H69N15O9 which containing 50 Carbon atoms,69 Hydrogen atoms,15 Nitrogen atoms and 9 Oxygen atoms,and the molecular weight of  Melanotan II is 1024.19.

5.What is Melanotan II (121062-08-6) used for?

Melanotan II is a synthetic analogue of the melanocortin peptide hormone alpha-melanocyte stimulating hormone (α-MSH) that occurs naturally. In usage, Melanotan II has been revealed to have aphrodisiac and melanogenesis (tanning) effects that have been subjected to clinical trials and preliminary studies. The compound is a cyclic lactam analogue of α-MSH that has an amino sequence named MTII (Ac-Nle-c[Asp-His-D-Phe-Arg-Trp-Lys]-NH2). Notably, no government drug regulatory agency across the world had approved for the use of any compound incorporating the Melanotan II peptide by 2010

InChI:InChI=1/C50H71N15O10/c1-3-4-16-36(59-29(2)66)44(70)65-41(25-42(67)68)49(75)64-40(24-32-27-55-28-58-32)48(74)62-38(22-30-13-6-5-7-14-30)46(72)61-37(19-12-21-56-50(53)54)45(71)63-39(23-31-26-57-34-17-9-8-15-33(31)34)47(73)60-35(43(52)69)18-10-11-20-51/h5-9,13-15,17,26-28,35-41,57H,3-4,10-12,16,18-25,51H2,1-2H3,(H2,52,69)(H,55,58)(H,59,66)(H,60,73)(H,61,72)(H,62,74)(H,63,71)(H,64,75)(H,65,70)(H,67,68)(H4,53,54,56)/t35-,36-,37-,38+,39-,40-,41-/m0/s1

Relevant articles related to Melanotan II:

Article

Source

β-methylation of the Phe7 and Trp9 melanotropin side chain pharmacophores affects ligand-receptor interactions and prolonged biological activity

Haskell-Luevano, Carrie,Toth, Kate,Boteju, Lakmal,Job, Constatin,Castrucci, Ana Maria De L.,Hadley, Mac E.,Hruby, Victor J.

, p. 2740 - 2749 (1997)

Potent and Prolonged Acting Cyclic Lactam Analogues of α-Melanotropin: Design Based on Molecular Dynamics

Al-Obeidi, Fahad,Castrucci, Ana M. de L.,Hadley, Mac E.,Hruby, Victor J.

, p. 2555 - 2561 (2007/10/02)

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